SXR202205028B Spotlight:腫瘤代謝組學(xué)與腫瘤免疫治療(Cancer Cell)
文獻(xiàn)解讀
青山 ·2022年6月10日 13:31
LA induces PD-1 expression by Treg cells in highly glycolytic tumors
LA absorbed through MCT1 is a metabolic checkpoint of immune responses
MYC-amplified or liver metastatic tumors augment PD-1 + Treg cells with abundant LA
MCT1 highly expressed by Treg cells provides therapeutic target for immunotherapy